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Astraea

clinical trial automation · CDISC SDTM/ADaM

Founding Engineer

San Francisco Bay Area$150k–$300k/yrPosted 2 months ago
Software engineeringUnspecifiedFULL TIME
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Opens the source posting on ycombinator.com

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About the role

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We are looking for a founding engineer who wants to build deeply technical AI systems in one of the most important and regulated industries in the world.

You will work directly with the founders to

  • Build agentic workflows for clinical trial automation

  • Design reliable systems for document ingestion, data transformation, validation, and auditability

  • Own core product surfaces across frontend, backend, data infrastructure, and AI orchestration

  • Work closely with clinical teams to turn messy real-world workflows into production software

  • Ship quickly while maintaining the rigor required for regulated healthcare environments

You might be a fit if you

Are an exceptional full-stack or backend engineer

Care about building reliable, production-grade AI systems and can/have integrated into legacy systems in the past

Move fast, take ownership, and like ambiguous technical problems

Are excited by using AI to automate healthcare, clinical trials, or regulated data workflows

Want to join at the earliest stage and help define the engineering culture

We care less about credentials and more about raw ability, taste, speed, and ownership. This is a high-agency founding role for someone who wants to build category-defining software.

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