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Foresite Labs

AI for scientific discovery · biotech incubation

Senior Software Engineer

San Diego · OnsitePosted 1 month ago
Software engineeringSeniorFull Time
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SENIOR SOFTWARE ENGINEER

Location: San Diego, CA

Job Type: Full-Time

Salary: 146K – 155K

About THE Role

We are a startup building complex, performance-critical software and hardware systems at the intersection of instrumentation, algorithms, and data. We are looking for a Senior Software Engineer who is equally comfortable writing low-level C/C++ for embedded targets and building higher-level Python applications that tie a system together.

You will write production code that spans from device-level firmware interfaces up through orchestration software that coordinates the electrical, fluidic, and mechanical subsystems of a complex instrument. This is a hands-on engineering role for someone who likes working close to the hardware, enjoys making messy real-world systems behave predictably, and takes pride in clean, well-tested code.

You will work closely with hardware, firmware, algorithm, and application engineers to take instrument subsystems from prototype to production.

What You’ll DO

  • EMBEDDED & APPLICATION SOFTWARE DEVELOPMENT

  • • Write production-quality C/C++ for embedded targets and resource-constrained environments

  • • Build Python applications and services that orchestrate, monitor, and expose instrument behavior

  • • Develop and maintain device drivers, hardware abstraction layers, and communication interfaces (serial, USB, Ethernet, CAN, SPI, I2C)

  • • Bridge embedded subsystems and higher-level application logic through clean, well-defined interfaces

  • • Debug across the stack — from a misbehaving sensor or actuator up to an unhappy application thread

  • MULTI-COMPONENT SYSTEM ORCHESTRATION

  • • Design and implement the software that coordinates electrical, fluidic, and mechanical subsystems into a working instrument

  • • Build state machines and control loops that move the system through complex, multi-step protocols reliably

  • • Handle the realities of real-world hardware — timing, failure modes, recovery, calibration, interlocks, and safety

  • • Define interfaces and contracts between subsystem controllers, the orchestration layer, and the user-facing application

  • • Instrument the system so that when something goes wrong on a wet bench at 2am, the logs actually tell you why

  • LINUX & CONTAINERIZED WORKFLOWS

  • • Develop and deploy on Linux — both desktop and embedded

  • • Build and maintain Docker images and containerized workflows for development, testing, and deployment

  • • Manage build environments, dependencies, and reproducibility across developer machines and target hardware

  • • Debug system-level issues involving processes, devices, networking, and resource contention

  • ENGINEERING HYGIENE

  • • Write code that other engineers can read, extend, and trust — clear interfaces, sensible abstractions, useful tests

  • • Use git fluently for branching, review, bisecting, and clean history

  • • Participate in code review as a thoughtful reviewer and a graceful author

  • • Build small, sharp tools that make the team faster — not large frameworks that slow them down

What We’re Looking FOR

  • REQUIRED

  • • BS in Computer Science or Engineering with 5+ years or MS with 3+ years of professional software engineering experience building production systems

  • • Strong C/C++ skills, including comfort reading and debugging existing codebases

  • • 5+ years of Python experience and proven ability to design, build, and ship application-level software

  • • Hands-on experience with embedded development — talking to real hardware, working with constrained environments, and dealing with the failure modes that come with both

  • • Hands-on experience with application development — services, APIs, user-facing tools, or orchestration software

  • • Strong Linux skills: comfortable on the command line, debugging system behavior, and working with build toolchains

  • • Solid git fundamentals and good code hygiene — clear commits, readable diffs, useful tests, careful reviews

  • • Comfortable with Docker and containerized development and deployment workflows

  • STRONGLY PREFERRED

  • • Experience building multi-component orchestration software for systems that combine electrical, fluidic, and mechanical subsystems (instruments, lab automation, robotics, manufacturing equipment, or similar)

  • • Experience designing state machines or control software for multi-step physical protocols

  • • Comfort working alongside hardware, firmware, and mechanical engineers — and translating their constraints into software

  • • Experience with CI/CD pipelines and build systems (CMake, Make, or similar)

  • NICE-TO-HAVE

  • • Background in scientific instrumentation, biosensor platforms, lab automation, or medical devices

  • • Experience with real-time or near-real-time control software

  • • Familiarity with common embedded interfaces and protocols (Modbus, CANopen, EtherCAT, gRPC, MQTT, etc.)

  • • Experience in regulated development environments (FDA, ISO, or similar)

  • WHAT SUCCESS LOOKS LIKE

  • • Instrument subsystems behave predictably, recover gracefully, and are debuggable when they don’t

  • • The orchestration software is something other engineers want to build on — not something they work around

  • • Code you ship is reliable enough that the team trusts it, and clear enough that they can extend it without paging you

  • • Hardware, firmware, and application engineers can move faster because of the interfaces and tooling you build

  • • When a hard, cross-domain bug shows up, you are one of the people the team is glad to have on it

WHY Join US

• Work in a dynamic, collaborative environment where innovation and scientific rigor are deeply valued

• Join a seasoned, multidisciplinary team tackling high-impact problems at the intersection of science and engineering

• Competitive compensation and equity package, comprehensive benefits, and flexibility to support work-life integration

We are an equal opportunity employer. We thrive on diversity and collaboration.

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